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The Bioprecursor
ALZEX has developed innovative drug candidates called Bioprecursors.
Bioprecursor = Improved prodrug (drug de novo and not a simple delivery system).
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- Successful design of new drugs for AD modeling commercial FDA approved drugs
- Bioprecursor technology can be applied to other brain diseases (MULTI DRUG PLATFORM)
- Successful design of new drugs for AD modeling commercial FDA approved drugs
- Bioprecursor technology can be applied to other brain diseases (MULTI DRUG PLATFORM)
- Successful design of new drugs for AD modeling commercial FDA approved drugs
- Bioprecursor technology can be applied to other brain diseases (MULTI DRUG PLATFORM)
Module Technology: How it Works
Using ‘module technology’ drug assembly techniques, we start with an Active Pharmaceutical Ingredient (API) inspired from previous FDA approved drugs. (Old Technology)
We draw on the known drug’s action of FDA approved ingredients
We then add our proprietary IP for better penetration through the BBBand central vs peripheral selectivity (low level of side-effects)
We design a redox switch to trigger the molecule only once it is inside the brain
The Endgame: New API Activated
Typical AChe Inhibitor Rivastigmine (Exelon)
Protonated form - AChe recognition with side effects
Application of the BBB penetration Technology and the redox switch to trigger the molecule only once it is inside the brain.
Unprotanable nitrogenNo AChE recognition BIOPRESCURSOR
Application of the BBB penetration Technology and the redox switch to trigger the molecule only once it is inside the brain.
Fully charged nitrogenAChE recognition Active Form
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